Kamal Mehra (Anil Kapoor) is a businessman who owns Ayka, a company on the verge of bankruptcy. He has a troubled relationship with his wife, Neelam (Shefali Shah) and his two children, Ayesha (Priyanka Chopra) and Kabir (Ranveer Singh). The Mehra family also includes their pet dog Pluto (voiced by Aamir Khan). Ayesha owns a successful business of her own, but is unhappy with her marriage to Manav Sangha (Rahul Bose), a controlling, narcissistic husband who, together with his mother Smita (Zarina Wahab), hates Ayesha’s family. Kabir unwillingly participates in the family business even though he yearns to become a pilot.
In celebration of Kamal and Neelam’s 30th wedding anniversary, they invite their family and friends for a 10-day cruise across the Mediterranean. Among their invitees are the Sood family, consisting of businessman Lalit Sood (Parmeet Sethi), his wife Naina (Dolly Mattdo) and their daughter Noori (Riddhima Sud). Kamal and Neelam plan to get Kabir married to Noori, in exchange for Lalit investing in Ayka.
On the cruise, Kabir meets dancer Farah (Anushka Sharma) and begins a romantic relationship with her. Noori, on the other hand, is in love with Rana Khanna (Vikrant Massey), the son of Vinod (Manoj Pahwa) and Vandana (Preeti Mamgain). The Khannas, however, are sworn enemies with the Soods, so Kabir and Noori decide to manipulate their parents into believing that they are dating each other, while continuing with their respective relationships. Ayesha considers divorcing her husband, whom she believes is incompatible with her. Her parents, however, are staunchly against it as they believe it will dishonour the family. Meanwhile, Sunny Gill (Farhan Akhtar), the son of Kamal’s manager Amrish (Ikhlaque Khan), arrives on the ship. It is revealed that Sunny and Ayesha dated each other as teenagers. Kamal, who was unhappy with their relationship, arranged and paid for Sunny to study abroad to separate his daughter from Sunny. Ayesha realises that she still harbors feelings for Sunny who is now a successful journalist. He, unlike her husband, appreciates her strong personality and believes in female empowerment.