Three friends – Meet (Vivek Oberoi), Prem (Aftab Shivdasani) and Amar (Ritesh Deshmukh) – are all unhappily married and have unsatisfactory sex lives. Meet thinks that his wife Unatti (Karishma Tanna) is having an affair with her boss; Prem thinks that his wife Tulsi (Manjari Fadnis) doesn’t spend quality time with him and Amar feels that his wife Mamta (Sonalee Kulkarni) is more concerned about their son, Pappu.
One day, the men receive an invite from their college, SLUTS (Sri Lalchand University of Technology and Science), to attend their college reunion. Their wives don’t come with them, so the three decide to use the trip to get up to mischief in order to escape their unhappy marriages.
When they arrive, they find that everyone else is behaving in an overly conservative manner. This due to the fear of Principal Roberts (Pradeep Rawat), who hangs people naked on a tree if they disagree with his rules. They find out that a former student, Hardik (Suresh Menon), is in a mental asylum because of the principal’s deeds. Meanwhile, Prem meets one of his former teachers, Rose (Maryam Zakaria), and is attracted to her. Meet meets Marlow (Kainaat Arora) and is attracted to her. Amar meets Mary (Bruna Abdullah) and is attracted to her. The men begin to initiate affairs with the women, but soon find out that Rose, Mary and Marlow are relatives of the principal. The men’s wives later arrive at the college, intending on joining them at the reunion.
The trio receive an MMS message containing footage of each of them having sex, and succeed in hiding the video from their wives. They find out that it was Hardik who sent the video, and he blackmails them. Their task is to kill the principal in order to fulfill Hardik’s revenge, or else he will show the footage to their wives. They fail in killing him, so they decide to try to delete the videos off Hardik’s phone. They succeed and continue to spend time at the reunion.