The movie is set in a city in Goa, where Kabir “Rocky” Ahlawat (John Abraham) lives a quiet life running a pawn shop. His next door neighbor is Anna (Nathalia Kaur), a drug addict and bar dancer. She lives with her little daughter, Naomi, who develops a nurturing relationship with Rocky and affectionately calls him “Handsome.” Meanwhile, ACP Dilip from the Anti-Narcotics Department of the police force is after the drug kingpin, Mantoo. Mantoo is supported by two powerful brothers, Kevin and Luke, who not only deal drugs but also control a mass racket in organ harvesting with a professional assassin, Attila.
One night, Anna and her accomplice steal drugs from Mantoo’s henchman, Bigshow. Anna hides the drugs in a camera that she pawns to Rocky. The loss of the consignment enrages Mantoo and he gives Kevin three days to recover the stolen drugs. Luke and Attila reach Anna’s place, where Luke tortures Anna for the camera. Atilla finds Bigshow already fighting with Rocky for it. Rocky is obliged to hand over the camera to Luke when he tells him that both Naomi and her mother are his captives. Rocky gets a call from Kevin to make a delivery to Mantoo, and promises that in return he will set Anna and Naomi free. Rocky goes to deliver the drugs to Mantoo, where he finds that police had already raided Mantoo’s haven. Mantoo flees and Rocky chases him, but he is arrested by police. They are shocked to find Anna’s naked body with all her organs harvested in Rocky’s car. Kevin brutally murders Mantoo, taking all his organs, and becomes the new drug lord.